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Selected clinical trial

A Phase 2, Randomized, Open-label Study of VVD-133214 with Pembrolizumab versus Pembrolizumab Monotherapy in Advanced MSI-H/dMMR Colorectal Adenocarcinoma

Sponsor: Vividion Therapeutics Inc.

Phase: 2

Disease: Advanced colorectal adenocarcinoma, Metastatic colorectal cancer

EU trial number: 2026-525507-26-00

Population: Adults aged 18 years or older (19 in Japan and South Korea) with unresectable or metastatic colorectal adenocarcinoma, MSI-high and/or deficient mismatch repair confirmed locally, ECOG 0-1, measurable RECIST v1.1 disease, and no prior systemic therapy for metastatic disease.

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